Last update
5/25/2025
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
USERS' SCORE
Good
Based on 8 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin D3 (Cholecalciferol)
25 mcg (1,000 IU)
130%
Vitamin K K-2 (MK-4) (Menaquinone)
100 mcg
80%
Calcium (as dicalcium phosphate)
32 mg
2%

Top Medical Research Studies

8
Vitamin D3 improves cold symptoms
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.

Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.

Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
Read More
8
Vitamin D helps reduce cold symptoms
We conducted an insightful analysis to see how 25-hydroxyvitamin D, often referred to as 25OHD, impacts symptoms of upper respiratory tract infections, commonly known as colds. In this randomized, placebo-controlled study, participants with insufficient or deficient levels of vitamin D were given either a daily dose of 10 µg of 25OHD or a placebo over a period of 16 weeks. This setup allowed us to objectively compare the effects of vitamin D treatment.

Our findings were quite telling. We observed that those receiving 25OHD had significantly lower scores for physical symptoms such as runny nose, sneezing, and head congestion compared to the placebo group. Additionally, quality of life scores improved across the board for the vitamin D group, with the exception of one aspect—breathing easily.

However, it's important to note that while 25OHD intake seemed to alleviate some symptoms, there was no significant difference in the overall number of cold episodes experienced or the usage of medications like antibiotics and pain relievers. This suggests that while 25-hydroxyvitamin D can help reduce certain nasal symptoms and improve quality of life, it may not prevent colds or decrease their frequency.
Read More
We delved into the question of how vitamin D3 supplementation might influence occurrences of the common cold, particularly among athletes. There is growing interest within the sports nutrition community about whether certain nutrients can help maintain a healthy immune response during periods of intense physical training.

Our findings suggest that vitamin D3 is particularly important for immune function. Various studies indicate that adequate levels of vitamin D can assist in reducing the incidence and duration of infections, including colds, not just in athletes but in the general population, too. However, many individuals may experience low vitamin D levels, especially during the winter months when sunlight exposure is limited.

While the overall evidence suggests a beneficial role for vitamin D in immune health, we recognize that direct evidence specifically linking vitamin D3 to a reduction in the common cold is somewhat limited. Nonetheless, the importance of maintaining sufficient vitamin D status can't be overlooked in the broader context of overall health and resilience against infections.

In conclusion, while vitamin D3 shows promise in boosting our immunity, further focused research specifically addressing its impact on the common cold is needed for clearer insights.
Read More

Most Useful Reviews

8
Increased immunity
3 people found this helpful
As a result of the reception, I've noticed right away that my mood improves, lethargy and fatigue lessen, and my immunity increases, aiding my overall health and resistance to viruses and colds. Living near several factories with poor air quality, I've taken vitamin D3 and K2 as recommended by my therapist, and I am pleased with my health state!
Read More
10
Stronger immunity
After following my nutritionist's advice and taking Mason Natural K2 + D3, I noticed a significant improvement. My immunity strengthened, and I stopped catching colds every fortnight. I feel positive and energetic now. Minor health issues have vanished, likely due to enhanced immunity. Additionally, I found it easier to lose weight. My nutritionist suggested regular monitoring of vitamin D levels and prescribed it to maintain weight. I highly recommend these vitamins! However, consult specialists for suitable prescriptions.
Read More
9
Reduced cold risk
Vitamin D3 maintains the body's protective properties and reduces the risk of colds and viral diseases. Meanwhile, K2 enhances calcium absorption, essential for bone strength. With vitamin K2, calcium goes directly to the bones, avoiding deposits in blood vessels, joints, and kidneys.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
  • All Researches
We delved into the question of how vitamin D3 supplementation might influence occurrences of the common cold, particularly among athletes. There is growing interest within the sports nutrition community about whether certain nutrients can help maintain a healthy immune response during periods of intense physical training.

Our findings suggest that vitamin D3 is particularly important for immune function. Various studies indicate that adequate levels of vitamin D can assist in reducing the incidence and duration of infections, including colds, not just in athletes but in the general population, too. However, many individuals may experience low vitamin D levels, especially during the winter months when sunlight exposure is limited.

While the overall evidence suggests a beneficial role for vitamin D in immune health, we recognize that direct evidence specifically linking vitamin D3 to a reduction in the common cold is somewhat limited. Nonetheless, the importance of maintaining sufficient vitamin D status can't be overlooked in the broader context of overall health and resilience against infections.

In conclusion, while vitamin D3 shows promise in boosting our immunity, further focused research specifically addressing its impact on the common cold is needed for clearer insights.
Read More
9
Vitamin D3 shows potential benefits
We explored the potential benefits of a special combination of micronutrients, which includes vitamin D3, in helping individuals who frequently suffer from upper respiratory tract infections, commonly known as the common cold. This study involved 192 participants and was conducted as a randomized, placebo-controlled, double-blind trial over 16 weeks.

Our findings were promising, revealing that those in the group receiving the micronutrient blend reported significant improvements in their cold symptoms compared to those who received a placebo. Specifically, individuals with severe symptoms showed a notable reduction in their common cold scores, indicating that vitamin D3, along with other vitamins and minerals, could play a role in enhancing overall immune response.

Furthermore, younger participants in the active group were less likely to miss work due to cold episodes. Those who had low levels of vitamin D3 or vitamin C at the start of the study also experienced fewer episodes of illness, underscoring the importance of maintaining adequate levels of these nutrients.

While there was no isolated analysis of vitamin D3’s effectiveness, the overall improvement in the group suggests that this micronutrient, among others, could truly contribute to better health during cold season.
Read More
8
Vitamin D helps reduce cold symptoms
We conducted an insightful analysis to see how 25-hydroxyvitamin D, often referred to as 25OHD, impacts symptoms of upper respiratory tract infections, commonly known as colds. In this randomized, placebo-controlled study, participants with insufficient or deficient levels of vitamin D were given either a daily dose of 10 µg of 25OHD or a placebo over a period of 16 weeks. This setup allowed us to objectively compare the effects of vitamin D treatment.

Our findings were quite telling. We observed that those receiving 25OHD had significantly lower scores for physical symptoms such as runny nose, sneezing, and head congestion compared to the placebo group. Additionally, quality of life scores improved across the board for the vitamin D group, with the exception of one aspect—breathing easily.

However, it's important to note that while 25OHD intake seemed to alleviate some symptoms, there was no significant difference in the overall number of cold episodes experienced or the usage of medications like antibiotics and pain relievers. This suggests that while 25-hydroxyvitamin D can help reduce certain nasal symptoms and improve quality of life, it may not prevent colds or decrease their frequency.
Read More
8
Vitamin D3 improves cold symptoms
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.

Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.

Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
Read More
8
Micronutrients improve cold symptoms
We conducted an intriguing study focusing on how a combination of micronutrients, particularly vitamin D3, could affect the frequency and severity of common colds. The research involved 192 participants suffering from recurrent upper respiratory infections. It employed a randomized, placebo-controlled, double-blind design over 16 weeks to ensure reliability in results.

Our findings were quite enlightening. Participants who received the micronutrient combination, including vitamin D3, reported a significant improvement in their cold symptoms compared to those who got a placebo. Specifically, those in the active group experienced better symptom relief, especially among individuals who initially had severe cold symptoms or were younger than 45 years.

Additionally, the study revealed that those with low levels of vitamin D and vitamin C benefitted the most, reporting fewer episodes of common colds. We also noted an increase in serum levels of vitamin C, folic acid, and selenium in the active group, which correlated with reduced cold symptoms. However, while the data suggests benefits from vitamin D3 within the micronutrient combination, we can't exclusively attribute the positive results to vitamin D3 alone, as it was part of a larger group of nutrients.

Overall, this study offers promising insights into how enhancing our micronutrient intake might strengthen our immune responses to common colds, particularly for those prone to frequent infections.
Read More

User Reviews

USERS' SCORE
Good
Based on 8 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8
Increased immunity
3 people found this helpful
As a result of the reception, I've noticed right away that my mood improves, lethargy and fatigue lessen, and my immunity increases, aiding my overall health and resistance to viruses and colds. Living near several factories with poor air quality, I've taken vitamin D3 and K2 as recommended by my therapist, and I am pleased with my health state!
Read More
10
Stronger immunity
After following my nutritionist's advice and taking Mason Natural K2 + D3, I noticed a significant improvement. My immunity strengthened, and I stopped catching colds every fortnight. I feel positive and energetic now. Minor health issues have vanished, likely due to enhanced immunity. Additionally, I found it easier to lose weight. My nutritionist suggested regular monitoring of vitamin D levels and prescribed it to maintain weight. I highly recommend these vitamins! However, consult specialists for suitable prescriptions.
Read More
9
Reduced cold risk
Vitamin D3 maintains the body's protective properties and reduces the risk of colds and viral diseases. Meanwhile, K2 enhances calcium absorption, essential for bone strength. With vitamin K2, calcium goes directly to the bones, avoiding deposits in blood vessels, joints, and kidneys.
Read More
9
No colds
This supplement must have greatly aided my immune system; I haven't had a cold in years.
Read More
8
Faster recovery
I acquired excellent vitamin K2 to complement D3 as a preventative measure against colds. During the first days of illness, I doubled my dose, and along with other medications, my recovery was expedited. There were no allergies or digestive issues. I recommend purchasing this supplement.
Read More

Frequently Asked Questions

7
Strengthened nails
4 people found this helpful
I took Good D3 along with Nature's Bounty, Calcium, Magnesium and Zinc. The noticeable results appeared after about a month. My nails grew stronger and faster. I believe the combination with K2 aids in quicker absorption of D3 to the bones. With the lack of sun in St. Petersburg, this supplement has helped me avoid becoming severely ill during the common cold.
8
Increased immunity
3 people found this helpful
As a result of the reception, I've noticed right away that my mood improves, lethargy and fatigue lessen, and my immunity increases, aiding my overall health and resistance to viruses and colds. Living near several factories with poor air quality, I've taken vitamin D3 and K2 as recommended by my therapist, and I am pleased with my health state!
7.5
Supports immunity
I started taking it over two months ago and have found it beneficial. It supports my immunity during the common cold season.
10
Stronger immunity
After following my nutritionist's advice and taking Mason Natural K2 + D3, I noticed a significant improvement. My immunity strengthened, and I stopped catching colds every fortnight. I feel positive and energetic now. Minor health issues have vanished, likely due to enhanced immunity. Additionally, I found it easier to lose weight. My nutritionist suggested regular monitoring of vitamin D levels and prescribed it to maintain weight. I highly recommend these vitamins! However, consult specialists for suitable prescriptions.
9
No colds
This supplement must have greatly aided my immune system; I haven't had a cold in years.
8
Faster recovery
I acquired excellent vitamin K2 to complement D3 as a preventative measure against colds. During the first days of illness, I doubled my dose, and along with other medications, my recovery was expedited. There were no allergies or digestive issues. I recommend purchasing this supplement.
8
Vitamin D3 improves cold symptoms
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.

Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.

Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
8
Micronutrients improve cold symptoms
We conducted an intriguing study focusing on how a combination of micronutrients, particularly vitamin D3, could affect the frequency and severity of common colds. The research involved 192 participants suffering from recurrent upper respiratory infections. It employed a randomized, placebo-controlled, double-blind design over 16 weeks to ensure reliability in results.

Our findings were quite enlightening. Participants who received the micronutrient combination, including vitamin D3, reported a significant improvement in their cold symptoms compared to those who got a placebo. Specifically, those in the active group experienced better symptom relief, especially among individuals who initially had severe cold symptoms or were younger than 45 years.

Additionally, the study revealed that those with low levels of vitamin D and vitamin C benefitted the most, reporting fewer episodes of common colds. We also noted an increase in serum levels of vitamin C, folic acid, and selenium in the active group, which correlated with reduced cold symptoms. However, while the data suggests benefits from vitamin D3 within the micronutrient combination, we can't exclusively attribute the positive results to vitamin D3 alone, as it was part of a larger group of nutrients.

Overall, this study offers promising insights into how enhancing our micronutrient intake might strengthen our immune responses to common colds, particularly for those prone to frequent infections.
8
Vitamin D helps reduce cold symptoms
We conducted an insightful analysis to see how 25-hydroxyvitamin D, often referred to as 25OHD, impacts symptoms of upper respiratory tract infections, commonly known as colds. In this randomized, placebo-controlled study, participants with insufficient or deficient levels of vitamin D were given either a daily dose of 10 µg of 25OHD or a placebo over a period of 16 weeks. This setup allowed us to objectively compare the effects of vitamin D treatment.

Our findings were quite telling. We observed that those receiving 25OHD had significantly lower scores for physical symptoms such as runny nose, sneezing, and head congestion compared to the placebo group. Additionally, quality of life scores improved across the board for the vitamin D group, with the exception of one aspect—breathing easily.

However, it's important to note that while 25OHD intake seemed to alleviate some symptoms, there was no significant difference in the overall number of cold episodes experienced or the usage of medications like antibiotics and pain relievers. This suggests that while 25-hydroxyvitamin D can help reduce certain nasal symptoms and improve quality of life, it may not prevent colds or decrease their frequency.
We delved into the question of how vitamin D3 supplementation might influence occurrences of the common cold, particularly among athletes. There is growing interest within the sports nutrition community about whether certain nutrients can help maintain a healthy immune response during periods of intense physical training.

Our findings suggest that vitamin D3 is particularly important for immune function. Various studies indicate that adequate levels of vitamin D can assist in reducing the incidence and duration of infections, including colds, not just in athletes but in the general population, too. However, many individuals may experience low vitamin D levels, especially during the winter months when sunlight exposure is limited.

While the overall evidence suggests a beneficial role for vitamin D in immune health, we recognize that direct evidence specifically linking vitamin D3 to a reduction in the common cold is somewhat limited. Nonetheless, the importance of maintaining sufficient vitamin D status can't be overlooked in the broader context of overall health and resilience against infections.

In conclusion, while vitamin D3 shows promise in boosting our immunity, further focused research specifically addressing its impact on the common cold is needed for clearer insights.

References

  1. Shimizu Y, Ito Y, Uotsu N, Yui K. Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study. Nutrients. 2020;12. 10.3390/nu12123769
  2. Shimizu Y, Ito Y, Yui K, Egawa K, Orimo H. Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study. J Nutr Health Aging. 2018;22:491. 10.1007/s12603-017-0952-x
  3. Gleeson M. Immunological aspects of sport nutrition. Immunol Cell Biol. 2016;94:117. 10.1038/icb.2015.109
  4. Schmidt K, Zirkler S. [Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled double-blind study]. MMW Fortschr Med. 2011;153 Suppl 3:83.
  5. Schmidt K, Zirkler S. [Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled doubleblind study.]. MMW Fortschr Med. 2011;153:83. 10.1007/s15006-011-1630-2
image